Primary biliary cirrhosis, also known as a disorder that is more common in women today than in men, is characterized by inflammation of the small bile duct located in the liver. It occurs due to inflammation, swelling or chronic inflammation of the bile ducts, which are responsible for transporting bile fluid from the liver to the gallbladder. On the other hand, the bile ducts are damaged, so the accumulated bile and various substances begin to damage the liver. Primary biliary cirrhosis, on the other hand, causes inflammation in the bile ducts in the liver, initiating damage to the liver. What is primary biliary cirrhosis, and what are the symptoms of primary biliary cirrhosis primary biliary cirrhosis causes, what are the complications of primary biliary cirrhosis, primary biliary cirrhosis, such as how to treat many questions, where the “primary biliary cirrhosis” titled In this article you can find lots of information about the stages of primary biliary cirrhosis.
Contents
- What is Primary Biliary Cirrhosis?
- What are the Symptoms of Primary Biliary Cirrhosis?
- What Causes Primary Biliary Cirrhosis?
- What are the Complications of Primary Biliary Cirrhosis?
- Osteoporosis (Bone Resorption)
- Vitamin Deficiencies
- Gallstones
- Fat Absorption Disorder
- Jaundice
- Cirrhosis of the Liver
- Liver Cancer
- Liver Failure
- What Are the Stages of Development of Primary Biliary Cirrhosis?
- How is Primary Biliary Cirrhosis Treated?
What is Primary Biliary Cirrhosis?
Primary biliary cirrhosis, known as a gradual chronic liver disease that makes serious complications such as liver failure possible over time, is a disease that threatens women more and more today. Primary biliye cirrhosis, which damages the bile ducts in the liver, will naturally again directly affect the liver. All accumulated bile fluid or other toxic substances cause permanent wounds and cirrhosis. Primary biliary cirrhosis disease is considered an important liver disease because the inability to give a clear life expectancy to a person may vary depending on the general health status of the patient.
What are the Symptoms of Primary Biliary Cirrhosis?
Symptoms of primary biliary cirrhosis, especially pain in the abdomen, muscles and joints November;
- Itching on the skin
- Exhaustion
- Jaundice
- The presence of diarrhea
- Darkening of the skin color
- The occurrence of dryness in the eyes and lips
- Loss of appetite
- Cracks in the bones, etc. (osteoporosis)
- Losing weight
- The presence of edemas
- Cholesterol elevation
- Seeing mental changes
They are small yellow or white bumps called “xanthomas” on the skin and in custody.
What Causes Primary Biliary Cirrhosis?
Primary biliary cirrhosis, which is included in the classification of autoimmune diseases, is a disease that occurs when the immune system perceives and attacks liver tissues as foreign or harmful. Because; our immune system is a system that serves to destroy all harmful “components” such as bacteria or viruses. These protective cells, called T cells, damage the cells in the bile duct when they attack the liver and trigger the appearance of primary biliary cirrhosis. The reason for this “attacking” situation, which develops due to genetic and environmental factors, has still not been fully solved. However, if you are between the ages of 30 and 60, if you have a relative with primary biliary cirrhosis, if you smoke, it would be correct to say that you have a risk Deciency for primary biliary cirrhosis.
What are the Complications of Primary Biliary Cirrhosis?
It is very important to look at the complications brought about by primary biliary cirrhosis disease in more detail and to see to what extent it affects the disease.
Osteoporosis (Bone Resorption)
Osteoporosis, also known as bone resorption disease, is a disease that has not yet been linked to primary biliary cirrhosis. However, the most common complication of primary biliary cirrhosis is osteoporosis.
Vitamin Deficiencies
With the disruption of bile flow, fat digestion and absorption are disrupted. In addition, deficiencies in fat-soluble vitamins A, D, E and vitamin K are common in primary biliary cirrhosis.
Gallstones
Gallstone formation may be observed in patients with primary biliary cirrhosis. Therefore, your doctor may prescribe medications that will help prevent the formation of stones.
Fat Absorption Disorder
Fat absorption disorders that cause fat accumulation under the skin, which is typically visible around the joints and eyes, are seen in primary biliary cirrhosis. In addition to this symptom, which is observed in October primary biliary cirrhosis, diarrhea, fatty stools and sudden weight loss are also observed.
Jaundice
Jaundice, which is observed when primary biliary cirrhosis is very advanced and the liver disrupts its normal working order, manifests itself with yellowing of the skin and eyes.
Cirrhosis of the Liver
In the case of progression of primary biliary cirrhosis, the final stage is the cirrhosis stage. The entire liver is damaged and the risk of liver failure begins.
Liver Cancer
People diagnosed with primary biliary cirrhosis every 6 and 12. During the months, he should definitely come for liver cancer control. Because these checks are very important for detecting the first stages of liver cancer earlier and stopping cancer.
Liver Failure
The treatment of liver failure caused by primary biliary cirrhosis is only possible with liver transplantation.
What Are the Stages of Development of Primary Biliary Cirrhosis?
Depending on how much it affects the liver, 4 stages of primary biliary cirrhosis have been identified. In the first stage, there is inflammation and damage to the walls of the bile ducts, while in the second stage, the small bile ducts and surrounding liver cells are affected by the event. In the third stage, the prevalence of damage expands and shows the effect of the disease on a wider area of the liver. The last stage is also encountered with cirrhosis. That is, in the last stage, the benefits and harms in the liver are now “permanent”.
How is Primary Biliary Cirrhosis Treated?
The form of treatment for primary biliary cirrhosis is aimed at preventing liver damage whenever possible and reducing the symptoms in the patient. With the drug treatment designated as ursodeoxycholic acid or UDCA, the “natural bile acid” that supports the movement of bile to the liver and small intestine is provided to the body. After treatment with this drug, which helps reduce liver damage, your doctor may also prescribe medication for existing symptoms. Most of the drugs prescribed for many purposes, such as dry eyes, itching, dry mouth, and immunosuppressants, are intended to prevent symptoms and progression of the disease in the body.